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The story is set in the year 2707. The film\'s version of the world is that of the Mutant Chronicles role-playing game, where nearly everything is powered by steam, mankind has exhausted Earth’s natural resources. Four corporations have taken over the world in which they are constantly at war with one another, the Bauhaus, the Mishima, the Capitol and the Imperial. During a battle between two of the corporate forces, an ancient machine is unburied and mutants swarm the world. A team of unlikely heroes set off to destroy the machine and save mankind.

Mitch Hunter and Nathan Rooker, battle hardened Capitol soldiers, fight a desperate battle against a Bauhaus advance. When an errant shell destroys an ancient stone seal, they find themselves facing a new enemy: hideous necro-mutants, with bone blades that grow from their arms. Mitch barely manages to escape. Nathan does not.

The mutants multiply by millions and destroy all before them. The corporations\' leader, Constantine, is about to abandon the planet and leave countless innocents to their desperate fate, when he is approached by Brother Samuel, leader of the Brotherhood, an ancient monastic order.

Samuel is keeper of the Chronicles, a book that prophesies both the rise of the mutants, and the \'Deliverer\' that will destroy them. Samuel believes he is that Deliverer destined to journey deep into the earth and destroy the source of the mutant scourge.

He manages to recruit Mitch, along with a handful of like-minded soldiers: Steiner, honor bound Bauhaus officer; sword wielding Severian; street fighter El Jesus; fearless beauty Duval; and stoic warrior Juba.

"Mutant Chronicle" follows Mitch and Samuel\'s mission to venture into the very heart of the darkness in an attempt to save the planet from marauding hordes of deathless mutants.